Vitamin E overdose

Vitamin E is considered safe even in large doses. Doses over 536 mg (800 IU) may lead to an increased risk of bleeding, diarrhea, abdominal pain, fatigue, reduced resistance to bacterial infection and transiently raised blood pressure.

Some research suggests that vitamin E may actually be pro-oxidant at high doses; that is, may actually increase free radical damage.
Vitamin E overdoseThe results of a 1997 study done in Scotland showed that red cells of nonsmokers receiving 1050 mg of vitamin E had an increased susceptibility to peroxidation.
Also, prolonged supplementation with vitamin E led to a decline in vitamin C concentrations in the blood.



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