Niacin absorption and metabolism
Niacin is absorbed in the small intestine, mostly in the form of NAD or NADP. These compounds are then broken down to form nicotinamide which can be converted by bacteria to nicotinic acid. As niacin is water soluble, excess is excreted in the urine, although small amounts may be stored in the liver.
The amino acid, tryptophan, is converted to niacin in the body if sufficient iron, riboflavin and vitamin B6 are present. More than half the RDA for niacin can be obtained through the conversion of tryptophan.
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