Chromium overdose, toxic effects of excess intake
Little is known about the toxic effects of large doses of the form of chromium found in food and supplements. There have been reports of adverse effects, including irregular heartbeat, with people t
aking above the recommended 250 mcg dose.
A 1995 study found that chromium supplements caused severe damage to chromosomes of cells grown in the laboratory.However, no studies have yet been done to confirm these potential carcinogenic effects.
As toxic effects were not seen with other forms of chromium; including chromium nicotinate, nicotinic acid, and chromium chloride hexahydrate; the researchers concluded that the toxic effects were due to the picolinate part of the molecule.
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